Hubungan Gagal Ginjal Kronik Tingkat 4 Dan 5 Dengan Kejadian Dislipidemia Pada Pasien Gagal Ginjal Kronik Di Rumah Sakit Umum Pusat Fatmawati Periode Tahun 2016

Dimas Farhan Wibawanto, Salman Paris, Maria Selvester Thadeus

Sari


Dyslipidemia is a common complication of chronic kidney disease. Dyslipidemia itself is a common risk for a cardiovascular disease, which is the leading cause of death in chronic kidney disease. This study aims to identify the relationship of chronic kidney disease stage 4 and 5 with the incidence of dyslipidemia at Fatmawati General Hospital in the period of 2016. Design cross-sectional with simple random sampling technique. Data were collected by looking at the patient's medical records. Respondents are 80 people. The study population were all patients diagnosed with chronic kidney disease at Fatmawati Central General Hospital in 2016. The results showed that most chronic kidney disease stage 4 has normal level of low density lipoprotein as many 22 people (73.33%) while at stage 5 most have high level of low density lipoprotein high as many 36 people (72%). High density lipoprotein obtained in patients with chronic kidney disease stage 4 mostly had normal level as many 20 people (66.67%) for stage 5 mostly had low level as many 33 people (66%). Mean lipid values of triglyceride X̄ = 152,36, high density lipoprotein X̄ = 39,36 and low density lipoprotein X̄ = 145,01. Result of bivariate analysis with chi square test showed significant relationship of chronic kidney disease stage 4 and 5 with incidence of dyslipidemia (p = 0,002).

Kata Kunci


Gagal Ginjal Kronik; Dislipidemia, Lipid

Teks Lengkap:

PDF

Referensi


Badan Penelitian dan Pengembangan Kesehatan, Riset Kesehatan Dasar (RISKESDAS) 2013, Jakarta: Kementerian Kesehatan Republik Indonesia; 2013

Jeffrey, MS, Mark, M, Mitsnefes, Joseph, T, Flynn, Jens, G, Juan CK, Bradley, A, Warady, Susan LF. Dyslipidemia in Children with Chronic Kidney Disease; 2010. Kidney International. 2010 78(11):1154-63. Available from http://www.kidney-international.theisn.org/article/S0085-2538(15)54439-6/pdf. [Accessed Febuari 18, 2018]

Joseph, N, Matthew, W, The Unique Character of Cardiovascular Disease in Chronic Kidney Disease and Its Implications for Treatment with Lipid-Lowering Drugs; 2007. Clinical Journal of the American Society of Nephrology. 2007 2(4): 766-785. Diakses tanggal 27 Agustus Available from http://cjasn.asnjournals.org/conten/2/4/766.full. [Accessed Agustus 10 , 2017]

Kwan, CHB, Klonernberg, F, Beddu, S, Cheung, AK. Lipoprotein Metabolism and Lipid Management in Chronic Kidney Disease, J Am Soc Nephrol, 2007 18(4):1246-1261, Available from https://www.ncbi.nlm.nih.gov/pubmed/17360943. [Accesed April 3, 2018]

Robert, T, Sedo, R. Chronic Kidney Disease and Its Complications; 2008. Primary Care, 2008 35(2):329-44. Available from https://www.nature.com/articles/ndp201788. [Accessed Agustus 12, 2017]

Sathiyanarayanan, S, Shankar, MP, Prabhakar, R. Serum Lipid Profile in Chronic Renal Failure and Haemodialysis Patients. Journal Of Current Trends In Clinical Medicine & Laboratory Biochemistry; 2013 1(3):36-41. Available from

http://jctmb.com/Vol1-Issue3-OctDec2013/06.Serum%20lipid%20pofile%20in%20chronic%20renal20failur%20&%20hemodialysis%0patients.pdf. [Accesed Maret 1, 2018]

Stefano, DV, Maria, AR, Massimo, RM, Graziana, L. Dyslipidemia And Chronic Kidney Disease: A Focus On Pathogenesis And Treatment;2014.Clinical Lipidolgy; 2014 9[6]: 673-681, Available from https://www.tandfonline.com/doi/abs/10.2217/clp.14.45. [Acessed Maret 2, 2018]

Tannock, L 2015, Dyslipidemia in Chronic Kidney Disease, Endotext, Lexington

Vasilis, T, Elisaf, M. Dyslipidemia Associated with Chronic Kidney Disease; 2011. The Open Cardiovascular Medicine Journal, 2011 5: 41–48. Februari 2011, Available from

https://www.ncbi.nlm.nih.gov/pm articles/PMC3106357/. [Acessed Maret 2, 2018]

Visconti, L, Benvega, S, Lacquaniti, A, Cernaro, V, Bruzzse, A, Conti, G, Buemi, M , Santoro, D. Lipid Disorders in Patients with Renal Failure: Rolein Cardiovascular Events and Progression of Chronic Kidney Disease;2016. Journal of Clinical & Translational Endocrinology, 2016 6:8-14. Available from

http://www.sciencedirect.com/science/article/pii/S2214623716300217. [Acessed Maret 2, 2018]




DOI: http://dx.doi.org/10.33533/jpm.v12i2.296

Article Metrics

Sari view : 219 times
PDF - 61 times

Refbacks

  • Saat ini tidak ada refbacks.


##submission.copyrightStatement##

 


width="113"

Gedung Wahidin Sudirohusodo, UPN Veteran Jakarta                     

Jl. RS Fatmawati No 1, Pondok Labu, Jakarta Selatan

Phone: 021-7656904 ; Fax: 021-7692860