DAYA HAMBAT EKSTRAK BIJI JINTAN HITAM (Nigella sativa Linn.) TERHADAP PERTUMBUHAN Candida albicans

Authors

  • Siti Maryam Istiqomah
  • Agus Aulung
  • Luh Eka Purwani

DOI:

https://doi.org/10.33533/jpm.v9i1.822

Keywords:

Biji jintan hitam, Candida albicans, Ekstrak, Metode difusi

Abstract

Infectious disease caused by candida is called Candidiasis and the species that mostly causes candidiasis is Candida albicans. Some fungal drugs have side effects that evoke discomfort, such as gastrointestinal disorde. Black cumin seed is traditional medicine that contains thymoquinoneas tha main indigredient that acts as an antifungal. This study was designed to study the antifungal inhibition activity of black cumin seed (N. sativa Linn) extract againts Candida albicans growth. This study used an experimental laboratory with the in vitro diffusion method in Sabouraund dextrose agar in order to observe and measure growth inhibition. Black cumin seed extract was obtained from Research Institute for Medicinal an Aromatic Plants (BALITRO) Bogor. The study showed that growth inhibition by the following concentration 100, 80, 60, 40, 20 and 10% with the mean of inhibition activity were 9.00; 4.83; 2.87; 2.49 and 0.19 mm. the data were analyzed by using alternative test and showed the probability score value of p < 0.05. It was concluded that black cumin seed extract had inhibition activity againts Candida albicans growth in vitro.

Author Biographies

Siti Maryam Istiqomah

Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta

Agus Aulung

Fakultas Kedokteran Universitas Indonesia      

Luh Eka Purwani

Fakultas Kedokteran Universitas Pembangunan Nasional “Veteran” Jakarta

References

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Ajizah A. Sensitivitas Salmonella thypimurium terhadap ekstrak daun Psidium guajava L. Diunduh dari http://bioscientie.unlam.ac.id/v1n1_ajizah.pdf. Diakses pada tanggal 8 Juni 2013.

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Sotya P, Erni S, Agnes SS, Satiti RP. Kolonisasi Candida pada Penggunaan Kontrasepsi Hormonal dan Non-hormonal (Penelitian Pendahuluan). J Mikol Kedokteran Indonesia. 2010; 7: 4-6.

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Published

2019-05-24

How to Cite

Istiqomah, S. M., Aulung, A., & Purwani, L. E. (2019). DAYA HAMBAT EKSTRAK BIJI JINTAN HITAM (Nigella sativa Linn.) TERHADAP PERTUMBUHAN Candida albicans. Jurnal Profesi Medika : Jurnal Kedokteran Dan Kesehatan, 9(1). https://doi.org/10.33533/jpm.v9i1.822

Issue

Vol. 9 No. 1 (2015): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan

Section

Case Study

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