Limpasu Pericarpium : an Alternative Source of Antioxidant From Borneo with Sequential Maceration Method

Irfan Zamzani, Nita Triadisti

Abstract


Antioxidants are substances that can slow down the oxidation process of free radicals. Limpasu plant (Baccaurea lanceolata (Miq) Muell. Arg), an indigenous plant of Borneo, is a natural antioxidant source. The purpose of this study was to determine the antioxidant activity of the limpasu pericarpium extract. The extraction of the limpasu pericarpium was done by maceration method using solvents with increasing polarity ranging from n-hexane, ethyl acetate, and methanol. Antioxidant activities of the three extracts were measured by the DPPH and FRAP methods. The IC50 values of n-hexane, ethyl acetate, and methanol extracts, as well as quercetin using the DPPH method were 517,45 µg/mL, 530,64 µg/mL, 10,63 µg/mL and 6,83 µg/mL, respectively. Meanwhile, the IC50 values obtained from FRAP method were 198,96 µg/mL, 190,07 µg/mL, 661,36 µg/mL, and 7,09 µg/mL, respectively. The results revealed that the methanol extract is more potent than other extracts tested for antioxidant activity.


Keywords


Baccaurea lanceolate; Antioxidant; DPPH; FRAP

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References


Chiva-Blanch G, Visioli F. Polyphenols and health: Moving beyond antioxidants. J Berry Res. 2012;2(2):63–71.

Battino M, Beekwilder J, Denoyes-Rothan B, Laimer M, McDougall GJ, Mezzetti B. Bioactive compounds in berries relevant to human health. Nutr Rev. 2009;67(SUPPL. 1).

Tenore GC, Novellino E, Basile A. Nutraceutical potential and antioxidant benefits of red pitaya (Hylocereus polyrhizus) extracts. Vol. 4, Journal of Functional Foods. 2012. p. 129–36.

Boeing H, Bechthold A, Bub A, Ellinger S, Haller D, Kroke A, et al. Critical review: Vegetables and fruit in the prevention of chronic diseases. Eur J Nutr. 2012;51(6):637–63.

Giampieri F, Alvarez-Suarez JM, Mazzoni L, Forbes-Hernandez TY, Gasparrini M, Gonzàlez-Paramàs AM, et al. An anthocyanin-rich strawberry extract protects against oxidative stress damage and improves mitochondrial functionality in human dermal fibroblasts exposed to an oxidizing agent. Food Funct. 2014;5(8):1939–48.

Tilburt JC, Kaptchuk TJ. Herbal medicine research and global health: An ethical analysis. Bull World Health Organ. 2008;86(8):594–9.

Uluk A, Sudana M, Wollenberg E. Ketergantungan Masyarakat Dayak Terhadap Hutan. Indonesia: Center for International Forestry Research; 2001. 262 p.

Abu Bakar MF, Bakar A, Ahmad NE, Karim FA, Saib S. Phytochemicals and Antioxidative Properties of Borneo Indigenous Liposu (Baccaurea lanceolata) and Tampoi (Baccaurea macrocarpa) Fruits. Antioxidants. 2014;3:516–25.

Hadi S, Mangkurat UL, Wahyuono S, Mada. Earch Active Fraction Of Baccaurea Lanceolate Tapin District, South Kalimantan As Antioxidants. Pharmacy. 2018;12(2):242–6.

Fitriansyah SN, Yola Desnera Putri, Diah Lia Aulifa, Muhammad Haris, Yeni Agustina F. Aktivitas Antioksidan, Total Fenolik Dan Total Flavonoid Ekstrak Buah, Daun Dan Kulit Batang Limpasu (Baccaurea lanceolata). J Farm Galen. 2018;5(3):115–21.

Fitriansyah SN, Yola Desnera Putri, Muhammad Haris RF, Rita Nurhayati YPS. Aktivitas Antibakteri Ekstrak Etanol Buah, Daun, Dan Kulit Batang Limpasu (Baccaurea lanceolata (Miq.) Müll.Arg.) dari. Pharm J Indones. 2018;15(02):1–21.

Hadi S, Subagus Wahyuono, Ag. Yuswanto EL. SPF Test from Baccaurea lanceolata Muell . Arg Fruit Isolates. Indones J Cancer Chemoprevention. 2017;8(1):38–41.

Bobo-García G, Davidov-Pardo G, Arroqui C, Vírseda P, Marín-Arroyo MR, Navarro M. Intra-laboratory validation of microplate methods for total phenolic content and antioxidant activity on polyphenolic extracts, and comparison with conventional spectrophotometric methods. J Sci Food Agric. 2015;95(1):204–9.

Panda SK. Assay Guided Comparison for Enzymatic and Non-Enzymatic Antioxidant Activities with Special Reference to Medicinal Plants. In: Antioxidant Enzyme [Internet]. 2012. p. 381–400. Available from: https://www.intechopen.com/books/advanced-biometric-technologies/liveness-detection-in-biometrics

Xu D, Hu MJ, Wang YQ, Cui YL. Antioxidant activities of quercetin and its complexes for medicinal application. Molecules. 2019;24(6).

Zheng YZ, Deng G, Liang Q, Chen DF, Guo R, Lai RC. Antioxidant activity of quercetin and its glucosides from propolis: A theoretical study. Sci Rep [Internet]. 2017;7(1):1–11. Available from: http://dx.doi.org/10.1038/s41598-017-08024-8

Vásquez-Espinal A, Yañez O, Osorio E, Areche C, García-Beltrán O, Ruiz LM, et al. Theoretical Study of the Antioxidant Activity of Quercetin Oxidation Products. Front Chem. 2019;7(November):1–10.

Li Z, Teng J, Lyu Y, Hu X, Zhao Y, Wang M. Enhanced antioxidant activity for apple juice fermented with lactobacillus plantarum ATCC14917. Molecules. 2019;24(1):1–12.

Indarti K, Apriani EF, Wibowo AE, Simanjuntak P. Antioxidant Activity of Ethanolic Extract and Various Fractions from Green Tea (Camellia sinensis L.) Leaves. Pharmacogn J. 2019;11(4):771–6.

Kusmiati, Wijaya IGAK, Yadi. Uji potensi antioksidan ekstrak lutein bunga kenikir (Tagetes erecta) berwarna kuning dan jingga dengan metode FRAP dan DPPH Potency test of antioxidant lutein of marigold flower (Tagetes erecta) extract yellow and orange. Pros Sem Nas Masy Biodiv Indon. 2018;4(274–279):274–9.

Matyas M, Hasmasanu MG, Zaharie G. Antioxidant capacity of preterm neonates assessed by hydrogen donor value. Med. 2019;55(11):1–8.

Indradi RB, Fidrianny I, Wirasutisna KR. DPPH Scavenging Activities and Phytochemical Content of Four Asteraceae Plants. Int J Pharmacogn Phytochem Res. 2017;9(6):755–9.

Abarca-Vargas R, Peña Malacara CF, Petricevich VL. Characterization of chemical compounds with antioxidant and cytotoxic activities in bougainvillea x buttiana holttum and standl, (Var. rose) extracts. Antioxidants. 2016;5(4).

Haryoto, H., & Frista A. Aktivitas Antioksidan Ekstrak Etanol, Fraksi Polar, Semipolar dan Non Polar dari Daun Mangrove Kacangan (Rhizophora apiculata) dengan Metode DPPH dan FRAP. J Sains dan Kesehat. 2019;2(2):122–8.

Eweka OI, Austin Eromosele I NE and KOO. Journal of Phytomedicine and Therapeutics : JOPAT. J Phytomedicine Ther [Internet]. 2020;19(1):364–74. Available from: https://www.ajol.info/index.php/jopat/article/view/166599

Eom T, Kim E, Kim JS. In vitro antioxidant, antiinflammation, and anticancer activities and anthraquinone content from rumex crispus root extract and fractions. Antioxidants. 2020;9(8):1–13.

Salimikia I, Monsef-Esfahani HR, Gohari AR, Salek M. Phytochemical analysis and antioxidant activity of Salvia chloroleuca aerial extracts. Iran Red Crescent Med J. 2016;18(8):8–12.

Brunetti C, Di Ferdinando M, Fini A, Pollastri S, Tattini M. Flavonoids as antioxidants and developmental regulators: Relative significance in plants and humans. Int J Mol Sci. 2013;14(2):3540–55.

Procházková D, Boušová I, Wilhelmová N. Antioxidant and prooxidant properties of flavonoids. Vol. 82, Fitoterapia. 2011. p. 513–23




DOI: http://dx.doi.org/10.33533/jpm.v15i1.2820

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