Collodion Baby And Cholestasis: A Rare Case Report

Authors

  • Bagus Setyoboedi Universitas Airlangga
  • Rendi Aji Prihaningtyas Universitas Airlangga
  • Syania Mega Octariyandra Universitas Airlangga

DOI:

https://doi.org/10.33533/jpm.v18i1.7392

Keywords:

collodion baby, neonatal ichtyosis syndrome, cholestasis

Abstract

Collodion baby with cholestasis is an uncommon condition. The term "collodion baby" refers to newborns with thick skin covering their entire body. Neonatal cholestasis is a form of conjugated cholestasis hyperbilirubinemia caused by reduced bile flow. The condition causes persistent jaundice (over two weeks) and elevated conjugated bilirubin. Genetic abnormalities or gene mutations have been reported in neonatal ichthyosis syndrome with cholestasis.

A case report of a collodion baby, a rare congenital condition characterized by a parchment-like membrane covering the entire body, was brought to Dr. Soetomo General Academic Hospital. Prolonged jaundice was one of the other findings. A skin biopsy found characteristics consistent with the diagnosis of collodion in a newborn. The paediatric team managed this case, which was treated in collaboration with a dermatologist. This case showed that newborn collodion syndrome required skin care, cholestasis screening, and jaundice management from birth.

 

References

Bhatia V, Bavdekar A, Matthai J, Waikar Y, Sibal A. Management of neonatal cholestasis: Consensus statement of the pediatric gastroenterology chapter of Indian academy of pediatrics. Indian Pediatr. 2014 Mar;51(3):203–10. DOI: https://doi.org/10.1007/s13312-014-0375-2

Ranucci G, Della Corte C, Alberti D, Bondioni MP, Boroni G, Calvo PL, et al. Diagnostic approach to neonatal and infantile cholestasis: A position paper by the SIGENP liver disease working group. Digestive and Liver Disease. 2022 Jan;54(1):40–53. DOI: https://doi.org/10.1016/j.dld.2021.09.011

Feldman AG, Mack CL. Biliary Atresia: Clinical Lessons Learned. J pediatr gastroenterol nutr. 2015 Aug;61(2):167–75 DOI: https://doi.org/10.1097/MPG.0000000000000755.

Rodríguez-Pazos L, Ginarte M, Vega A, Toribio J. Autosomal Recessive Congenital Ichthyosis. Actas Dermo-Sifiliográficas (English Edition). 2013 May;104(4):270–84 DOI: https://doi.org/10.1016/j.adengl.2011.11.021.

Bezerra JA. The next challenge in pediatric cholestasis. Journal of Pediatric Gastroenterology and Nutrition. 2006 Jul;43(S1). DOI: https://doi.org/10.1097/01.mpg.0000228197.28056.2f

Liu X, Peng X, Huang Y, Shu C, Liu P, Xie W, et al. Design and validation of a noninvasive diagnostic criteria for biliary atresia in infants based on the STROBE compliant. Medicine. 2019 Feb;98(6):e13837 DOI: https://doi.org/10.1097/MD.0000000000013837.

Schwarz KB, Haber BH, Rosenthal P, Mack CL, Moore J, Bove K, et al. Extrahepatic Anomalies in Infants With Biliary Atresia: Results of a Large Prospective North American Multicenter Study: Schwarz et al. Hepatology. 2013 Nov;58(5):1724–31 DOI: https://doi.org/10.1002/hep.26512.

Simalti AK, Sethi H. Collodion Baby. Medical Journal Armed Forces India. 2017 Apr;73(2):197–9 DOI: https://doi.org/10.1016/j.mjafi.2015.10.007.

Fatnassi R, Marouen N, Ragmoun H, Marzougui L, Hammami S. Le Bébé Collodion: Aspects cliniques et intérêt du diagnostic anténatal. Pan African Medical Journal. 2017;26. DOI: https://doi.org/10.11604/pamj.2017.26.118.10025

Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, et al. Initial assessment of the infant with neonatal cholestasis—Is this biliary atresia? Alpini GD, editor. PLoS ONE. 2017 May 11;12(5):e0176275 DOI: https://doi.org/10.1371/journal.pone.0176275

Ağın M, Tümgör G, Alkan M, Özden Ö, Satar M, Tuncer R. Clues to the diagnosis of biliary atresia in neonatal cholestasis. Turk J Gastroenterol. 2016 Jan;27(1):37–41 DOI: https://doi.org/10.5152/tjg.2015.150379.

Fontenele JPU, Schenka AA, Hessel G, Jarry VM, Escanhoela CAF. Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies. Braz J Med Biol Res [Internet]. 2016 Mar [cited 2024 Jan 12];49(3). DOI : https://doi.org/10.1590/1414-431X20154808

Yang M, Chang M, Chiu S, Peng S, Wu J, Ni Y, et al. Implication of early‐onset biliary atresia and extrahepatic congenital anomalies. Pediatrics International. 2010 Aug;52(4):569–72 DOI: https://doi.org/10.1111/j.1442200X.2009.03014.x.

Sung S, Jeon TY, Yoo SY, Hwang SM, Choi YH, Kim WS, et al. Incremental Value of MR Cholangiopancreatography in Diagnosis of Biliary Atresia. Alpini GD, editor. PLoS ONE. 2016 Jun 24;11(6):e0158132 DOI: https://doi.org/10.1371/journal.pone.0158132.

Nguyen KD, Sundaram V, Ayoub WS. Atypical causes of cholestasis. WJG. 2014 Jul 28;20(28):9418–26 DOI: https://doi.org/10.3748/wjg.v20.i28.9418.

El-Guindi MAS, Sira MM, Sira AM, Salem TAH, El-Abd OL, Konsowa HAS, et al. Design and validation of a diagnostic score for biliary atresia. Journal of Hepatology. 2014 Jul;61(1):116–23 DOI: https://doi.org/10.1016/j.jhep.2014.03.016

Semwal P, Akhil Raj MS, Bhat NK, Verma PK. NISCH Syndrome as a cause of Neonatal Cholestasis - a case report from India. Journal of Clinical and Experimental Hepatology. 2022;12:S79 DOI: https://doi.org/10.1016/j.jceh.2022.07.192.

Nguyen MA, Gelman A, Norton SA. Practical events in the management of a Collodion Baby. JAMA Dermatology. 2015 Sept 1;151(9):1031. DOI: https://doi.org/10.1001/jamadermatol.2015.0694

Kelly DA, Davenport M. Current management of Biliary Atresia. Archives of Disease in Childhood. 2007 Dec 1;92(12):1132–5. DOI: https://doi.org/10.1136/adc.2006.101451

Downloads

Published

2024-06-15

How to Cite

Setyoboedi, B., Prihaningtyas, R. A., & Octariyandra, S. M. (2024). Collodion Baby And Cholestasis: A Rare Case Report. Jurnal Profesi Medika : Jurnal Kedokteran Dan Kesehatan, 18(1), 106–111. https://doi.org/10.33533/jpm.v18i1.7392

Issue

Vol. 18 No. 1 (2024): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan

Section

Case Study

Categories

License

Copyright (c) 2024 Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright Notice

All articles submitted by the author and published in the Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan, are fully copyrighted by the publication of Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan under the Creative Commons Attribution-NonCommercial 4.0 International License by technically filling out the copyright transfer agreement and sending it to the publisher

Note :

The author can include in separate contractual arrangements for the non-exclusive distribution of rich versions of journal publications (for example: posting them to an institutional repository or publishing them in a book), with the acknowledgment of their initial publication in this journal.

Authors are permitted and encouraged to post their work online (for example: in an institutional repository or on their website) before and during the submission process because it can lead to productive exchanges, as well as earlier and more powerful citations of published works. (See Open Access Effects).