Rapid Decline in the Uptake Interests for Different SARS CoV-2 Vaccination Doses Over the Post Vaccination Period in Different European Community Countries

Sudhir Bhatia

doi:10.33533/jpm.v17i2.6597

Authors

Sudhir Bhatia Genekam Biotechnology AG

DOI:

https://doi.org/10.33533/jpm.v17i2.6597

Keywords:

Vaccine Effectiveness, Uptake, SARS-CoV-2, Booster Dose

Abstract

During the corona virus pandemic outbreak, there are a number of vaccinations approved. They are distributed and used in human beings worldwide. Aim of this study is to analyze the changes in pattern of uptake mood during different dose courses in EU /EEA population. Therefore, there was use of the following methods: The data from official European community website was collected and analyzed with the software for total number of doses distributed and total number of doses applied. Similarly, cumulative percentage of uptake of vaccine from primary course, first booster, second booster and third booster were compared. Results are showing that there is difference of around 0.5 billion doses between the doses distributed and doses used. The uptake interest decreased from primary dose to third booster dose from 85% to 0% among the countries over the time. The conclusion was found as follows: there are discrepancies between the total number of doses distributed and used. There is very strong loss of uptake interest in the populations in EU/EEA with different dose courses. One must study the reasons for such a strong loss of uptake interest and economic losses caused leading to burden on the tax payers.

References

[1]. Amanna IJ, Slifka MK. Successful Vaccines. Curr Top Microbiol Immunol. 2020; 428:1-30. doi: 10.1007/82_2018_102.

[2]. Plotkin S. History of vaccination. Proc Natl Acad Sci U S A. 2014;111(34):12283-7. doi: 10.1073/pnas.1400472111.

[3]. Zhu, N. Zhang D, Wang W et al. A novel coronavirus from patients with pneumonia in China, 2019. N. Engl. J. Med. 2020;382:727–733. doi: 10.1056/NEJMoa2001017

[4]. Zhang J, Yu M, Tong S, Liu LY, Tang LV. Predictive factors for disease progression in hospitalized patients with coronavirus disease 2019 in Wuhan, China, Journal of Clinical Virology. 2020;127: 104392. doi: 10.1016/j.jcv.2020.104392

[5]. Adu P, Popoola T, Medvedev ON, Collings S, Mbinta J, Aspin C, Colin R. Simpson CR. Implications for COVID-19 vaccine uptake: A systematic review, Journal of Infection and Public Health. 2023;16(3):441-466. https://doi.org/10.1016/j.jiph.2023.01.020

[6]. McCabe SD, Hammershaimb EA, Cheng D et al. Unraveling attributes of COVID-19 vaccine acceptance and uptake in the U.S.: a large nationwide study. Sci Rep. 2023;13:8360. https://doi.org/10.1038/s41598-023-34340-3

[7]. Wang Q, Hu S, Du F et al. Mapping global acceptance and uptake of COVID-19 vaccination: A systematic review and meta-analysis. Commun Med. 2022;2:113. https://doi.org/10.1038/s43856-022-00177-6

[8]. Talmy T, Nitzan I. Rapid Rollout and Initial Uptake of a Booster COVID-19 Vaccine Among Israel Defense Forces Soldiers. J Prev (2022). 2023;44(1):1-14. doi: 10.1007/s10935-022-00702-2.

[9]. Shahid Z, Patrick AL, Wallander ML, Donahue EE, Trufan SJ, Tan AR, Hwang JJ, Burgess EF, Ragon B, Ghosh N, Grunwald MR, Voorhees PM, Copelan EA, Raghavan D. COVID-19 vaccine uptake trends in SARS-CoV-2 previously infected cancer patients. Vaccine X. 2023;14:100289. doi: 10.1016/j.jvacx.2023.100289.

[10]. Alcendor DJ, Matthews-Juarez P, Smoot D, Edwards A, Hildreth JEK, Juarez PD. Vaccine Confidence and Uptake of the Omicron Bivalent Booster in Tennessee: Implications for Vulnerable Populations. Vaccines (Basel). 2023;11(5):906. doi: 10.3390/vaccines11050906.

[11]. Cooper S, van Rooyen H, Wiysonge CS. COVID-19 vaccine hesitancy in South Africa: how can we maximize uptake of COVID-19 vaccines? Expert Rev Vaccines. 2021;20(8):921-933. doi: 10.1080/14760584.2021.1949291.

[12]. Aarstad J, Kvitastein OA. Is There a Link between the 2021 COVID-19 Vaccination Uptake in Europe and 2022 Excess All-Cause Mortality? Asian Pac. J. Health Sci., 2023;10(1):25-31.

[13]. European community vaccine track website: COVID-19 Vaccine Tracker | European Centre for Disease Prevention and Control (europa.eu) last visit Sept, 2023.

[14]. Khan K., Karim F., Cele S. et al. Omicron infection enhances Delta antibody immunity in vaccinated persons. Nature. 2022;607:356–359. https://doi.org/10.1038/s41586-022-04830-x

[15]. Fragwürdiger Impfstoff-Deal - wie Aufklärung verhindert wird Plusminus: Fragwürdiger Impfstoff-Deal - wie Aufklärung verhindert wird | ARD Mediathek, Last visit: 2 Sept, 2023