Clinical Characteristics of Ocular Toxoplasmosis Patients
DOI:
https://doi.org/10.33533/jpm.v17i1.5653Keywords:
Ocular toxoplasmosis, incidence, clinical characteristics.Abstract
Toxoplasma gondii infection causes posterior uveitis and blindness. The diagnosis of ocular toxoplasmosis is based on typical clinical findings accompanied by positive anti-Toxoplasma serology. This study aims to see the clinical characteristics of ocular toxoplasmosis patients. Cross-sectional observational descriptive research is done. This study used 2019-2021 medical records from RSUP Dr. Mohammad Hoesin Palembang patients. The highest incidence of ocular toxoplasmosis at RSUP Dr. Mohammad Hoesin Palembang in 2019-2021 occurred in 2021 (54.5%). The most common age range found in this case is the age group of 0-19 years (45.5%) and the majority are women (72.7%). The majority of patients are out of work (45.5%) and live outside Palembang (81.8%). The most lateralization was found in the right eye (63.6%). The most commonly complained clinical symptom is blurred vision (90.9%). Clinical signs were found lesions of retinochoroiditis in the macular (45,5%), in the extramacular (18,2%), chorioretinal scar (90,9%), vitritis (54,5%), decreased visual acuity (100%), and increased IOP (36,4%). Anti-Toxoplasma IgG was found positive in all patients. The highest incidence of ocular toxoplasmosis was found in 2021. The most commonly complained clinical symptom is blurred vision and the most commonly found clinical sign is a decrease in visual acuity.
References
Kalogeropoulos D, Sakkas H, Mohammed B, Vartholomatos G, Malamos K, Sreekantam S, et al. Ocular toxoplasmosis: a review of the current diagnostic and therapeutic approaches. Vol. 42, International Ophthalmology. Springer Science and Business Media B.V.; 2022. p. 295–321.
Garweg JG, Pleyer U. Treatment strategy in human ocular toxoplasmosis: Why antibiotics have failed. Vol. 10, Journal of Clinical Medicine. MDPI; 2021. p. 1–20.
Augsburger Riordan-Eva Paul JJ. Vaughan & Asbury’s general ophthalmology. 2018.
Dwianggita P. CASE REPORT Typically active ocular toxoplasmosis: a case report. DiscoverSys | Intisari Sains Medis [Internet]. 2020;11(3):1422–6. Available from: http://isainsmedis.id/
Retmanasari A, Widartono BS, Wijayanti MA, Artama WT. Prevalence and Risk Factors for Toxoplasmosis in Middle Java, Indonesia. Ecohealth. 2017 Mar 1;14(1):162–70.
Yanoff Duker Jay S. M. Ophthalmology. 2019.
Yu HG. Inflammatory and Infectious Ocular Disorders [Internet]. Springer Nature Singapore; 2019. (Retina Atlas). Available from: https://books.google.co.id/books?id=DJGyDwAAQBAJ
Pleyer U, Groß U, Schlüter D, Wilking H, Seeber F. Toxoplasmosis in Germany—epidemiology, diagnosis, risk factors, and treatment. Dtsch Arztebl Int. 2019 Jun 21;116(25):435–44.
Nida Sen H. 2021-2022 Basic and Clinical Science Course, Section 9: Uveitis and Ocular Inflammation. 2021.
Yang P. Atlas of Uveitis: Diagnosis and Treatment [Internet]. Springer Singapore; 2020. Available from: https://books.google.co.id/books?id=6KQLEAAAQBAJ
Matthew TJH, Zunaina E, Hussein A, Liza-Sharmini AT, Wan-Hazabbah WH, Shatriah I. Clinical profile of ocular toxoplasmosis in the Universiti Sains Malaysia hospital – 7-year review. Vol. 20, Family Medicine and Primary Care Review. Polish Society of Family Medicine; 2018. p. 13–6.
Sofia O, Hariyono RW. CLINICAL CHARACTERISTICS AND MANAGEMENT OF OCULAR TOXOPLASMOSIS. International Journal of Retina. 2019 Sep 18;2(2).
Shoukat T, Awan UA, Mahmood T, Afzal MS, Wasif S, Ahmed H, et al. Epidemiology of Toxoplasmosis among the Pakistani Population: A Systematic Review and Meta-Analysis. Pathogens. 2022 Jun 1;11(6).
Park SW, Kim SH, Kwon HJ, Lee SM, Byon IS, Lee JE. Diagnostic Value of Positive Findings of Toxoplasma gondii-Specific Immunoglobulin M Serum Antibody in Uveitis Patients to Confirm Ocular Toxoplasmosis. Ocul Immunol Inflamm [Internet]. 2019 May 19 [cited 2022 Nov 19];27(4):583–90. Available from: https://pubmed.ncbi.nlm.nih.gov/29513626/
Ajamil-Rodanes S, Luis J, Bourkiza R, Girling B, Rees A, Cosgrove C, et al. Ocular toxoplasmosis: phenotype differences between toxoplasma IgM positive and IgM negative patients in a large cohort. Br J Ophthalmol [Internet]. 2021 Feb 1 [cited 2022 Nov 19];105(2):210–5. Available from: https://pubmed.ncbi.nlm.nih.gov/32345603/
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