Capacity to Consent of People with Dementia: a Narrative Review from an Ethical Perspective


  • Urfa Khairatun Hisan - Faculty of Medicine, Universitas Ahmad Dahlan Yogyakarta. - Bioethics Master Study, Unversitas Gadjah Mada
  • Nurul Qomariyah Aff 1: Faculty of Medicine, Universitas Ahmad Dahlan, Yogyakarta, Indonesia Aff 2: Research Ethics Committee, Universitas Ahmad Dahlan, Yogyakarta, Indonesia
  • Kristina Elizabeth Aff 1: Graduate School of Health Law, Universitas Katolik Soegijapranata, Semarang, Indonesia Aff 2: Sector of Medical and Health Service, Resort Police Force of Yogyakarta, Indonesia



Capacity to Consent, Decision-making Capacity, Dementia, Research Ethics


People with dementia have impairment to execute daily life activities by presenting as a deterioration of mental processes, such as memory, thinking, reasoning, and judgment. Many participants in dementia research may lack the capacity to provide informed consent. Additional safeguards are needed for dementia research participants’ protection because of their vulnerability. Only after carefully weighing the risks and possible benefits for the participants in the research may it be decided to use vulnerable participants. The intention to prevent harm pushes against the removal of autonomy. This dilemma is the driving force behind this article's narrative review of the capacity to consent problems in dementia research. For this critical narrative review, we conducted a thorough search of Scopus, PubMed, and Wiley Open Library for literature addressing the ethical and legal issues on the capacity to consent of people with dementia. We outline the dilemmas and difficulties that surround them including the related ethical principles, the informed consent process, capacity to consent, and safeguards for the participant in research involving people with dementia.

Author Biography

Urfa Khairatun Hisan, - Faculty of Medicine, Universitas Ahmad Dahlan Yogyakarta. - Bioethics Master Study, Unversitas Gadjah Mada

Urfa Khairatun Hisan is a lecturer at the Faculty of Medicine, Universitas Ahmad Dahlan, and a graduate student of the Department of Bioethics, Universitas Gadjah Mada. She received her B.Med. and M.D. degrees from the Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia, in 2017 and 2019, respectively. Her research interests include public health and bioethics in medicine. She can be contacted at email: or


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How to Cite

Hisan, U. K., Qomariyah, N., & Elizabeth, K. (2022). Capacity to Consent of People with Dementia: a Narrative Review from an Ethical Perspective. Jurnal Profesi Medika : Jurnal Kedokteran Dan Kesehatan, 16(2).