Primary Giant Cell Tumor of Soft Tissue in The Female Breast
DOI:
https://doi.org/10.33533/jpm.v16i1.3204Keywords:
Giant cell tumor, Soft tissue, BreastAbstract
A giant cell tumor of soft tissue (GCT-ST) is a rare tumor composed of mononuclear and osteoclast-like multinucleated giant cells. It is a low-grade malignant potential tumor morphologically analog to a giant cell tumor of bone. The superficial and deep soft tissue of extremities is the most frequent site of this tumor which is cured by complete or radical resection. GCT-ST as a primary tumor in the female Breast is exceedingly rare. Presentation of osteoclast-like multinucleated giant cells in the breast tumor has been described in association with the variant of breast carcinoma. We report a case of primary GCT-ST arising in the female Breast without a relationship with the epithelial component. To the best of our knowledge, this is the fifth such case report, and only the second one occurred in a female under 50 years.
References
Kulkarni M, Joshi A, Patil V, Ansari T. Giant cell tumor of soft tissues of low malignant potential: A rare diagnosis on fine needle aspiration cytology. Journal of Cytology. 2016 ;33(2):106–8.
Coindre JM. New WHO classification of tumours of soft tissue and bone. Annales de pathologie. 2012;32(5 Suppl):S115-6.
Kishi S, Monma H, Hori H, Kinugasa S, Fujimoto M, Nakamura T. First case report of a huge giant cell tumor of soft tissue originating from the retroperitoneum. American Journal of Case Reports. 2018;19:642–50.
Mardi K, Sharma J. Primary giant cell tumour of soft parts - Report of a case with fine needle aspiration cytology and histology findings. Journal of Cytology. 2007;24(1):58.
May SA, Deavers MT, Resetkova E, Johnson D, Albarracin CT. Giant cell tumor of soft tissue arising in breast. Annals of Diagnostic Pathology. 2007;11(5):345–9.
Romics L, Mallon EA, Reid R, Cordiner CM, Doughty JC. Osteoclast-like giant cell tumor arising in the soft tissue of the breast: Report of a case. Surgery Today. 2009;39(1):48–51.
Shousha S, Sinnett HD. Chest Wall Tumors Presenting as Breast Lumps. Breast Journal. 2004;10(2):150–3.
Gaspar BL, Sharma S, Singh R, Vasishta RK. Primary giant cell tumor of the female breast: a diagnostic red herring with therapeutic implications. APMIS. 2017;125(1):32–7.
Saldanha P, Tak HN. Giant Cell Tumour of Soft Tissue – A Rare Neoplasm. J Clin Biomed Sci. 2014;4:326–9.
Chand K, Bhardwaj RK, Rappai TJ. Study of 7 cases of giant cell tumor of soft tissue. Medical Journal Armed Forces India. 2006;62(2):138–40.
Downloads
Additional Files
Published
How to Cite
Issue
Section
License
Copyright Notice
All articles submitted by the author and published in the Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan, are fully copyrighted by the publication of Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan under the Creative Commons Attribution-NonCommercial 4.0 International License by technically filling out the copyright transfer agreement and sending it to the publisher
Note :
The author can include in separate contractual arrangements for the non-exclusive distribution of rich versions of journal publications (for example: posting them to an institutional repository or publishing them in a book), with the acknowledgment of their initial publication in this journal.
Authors are permitted and encouraged to post their work online (for example: in an institutional repository or on their website) before and during the submission process because it can lead to productive exchanges, as well as earlier and more powerful citations of published works. (See Open Access Effects).
