Primary Giant Cell Tumor of Soft Tissue in The Female Breast


  • Dody Novrial Department of Anatomical Pathology Faculty of Medicine Universitas Jenderal Soedirman
  • Muhammad Yamsun Department of Surgery Faculty of Medicine Universitas Jenderal Soedirman



Giant cell tumor, Soft tissue, Breast


A giant cell tumor of soft tissue (GCT-ST) is a rare tumor composed of mononuclear and osteoclast-like multinucleated giant cells.  It is a low-grade malignant potential tumor morphologically analog to a giant cell tumor of bone.  The superficial and deep soft tissue of extremities is the most frequent site of this tumor which is cured by complete or radical resection.  GCT-ST as a primary tumor in the female Breast is exceedingly rare.  Presentation of osteoclast-like multinucleated giant cells in the breast tumor has been described in association with the variant of breast carcinoma.  We report a case of primary GCT-ST arising in the female Breast without a relationship with the epithelial component.  To the best of our knowledge, this is the fifth such case report, and only the second one occurred in a female under 50 years.


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How to Cite

Novrial, D., & Yamsun, M. (2022). Primary Giant Cell Tumor of Soft Tissue in The Female Breast. Jurnal Profesi Medika : Jurnal Kedokteran Dan Kesehatan, 16(1).