The Relationship Between Tumor Size Parameters and Carcinoembryonic Antigen (CEA) Levels in Colorectal Adenocarcinoma Based on Contrast-Enhanced Abdominal CT Scan

Dewa Putu Jaya Prasatya; Ni Nyoman Margiani; I Gusti Agung Gede Mahendra Wijaya; I Wayan Gede Artawan Eka Putra

doi:10.33533/jpm.v19i1.12265

Authors

Dewa Putu Jaya Prasatya Universitas Udayana
Ni Nyoman Margiani Program Studi Radiologi,Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia
I Gusti Agung Gede Mahendra Wijaya Program Studi Radiologi,Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia
I Wayan Gede Artawan Eka Putra Program Studi Ilmu Kesehatan Masyarakat, Fakultas Kedokteran, Universitas Udayana, Bali, Indonesia

DOI:

https://doi.org/10.33533/jpm.v19i1.12265

Keywords:

Colorectal adenocarcinoma; contrast-enhanced abdominal CT scan; tumor area; tumor thickness; CEA.

Abstract

Introduction: Colorectal adenocarcinoma is a common malignancy with high mortality. Carcinoembryonic Antigen (CEA) is widely used as a tumor marker, while contrast-enhanced CT scans provide tumor size parameters. The correlation between these parameters and CEA remains unclear.

Objective: To analyze the relationship between tumor area and thickness on contrast-enhanced CT scan and CEA levels in colorectal adenocarcinoma.

Methods: A retrospective cross-sectional study was conducted at RSUP Prof. Dr. I.G.N.G. Ngoerah (2018–2023) involving patients with available CT scan and CEA data. Pearson correlation and multivariate regression were applied.

Results: Tumor area showed a significant positive correlation with CEA (r = 0.513; p = 0.001), independent of age and sex. Tumor thickness was not significantly correlated (r = 0.196; p = 0.224).

Conclusion: Tumor area correlates significantly with CEA levels, whereas tumor thickness does not. Tumor area may serve as an additional indicator in colorectal cancer evaluation.

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