Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report

Dwitya Elvira


Coronavirus disease-19 (COVID-19) and Human Immunodeficiency Virus (HIV) were pandemic diseases that affected the healthcare system worldwide. Decline immune system in HIV and accompanying opportunistic infection may worsen the outcome and prognosis of COVID-19 infection. Comprehensive diagnosis and treatment were crucial with HIV patients with a very low immune response. This is our first case report of 50 years old man recently known with HIV and confirmed COVID-19 from PCR swab at once. We found several comorbidities through a comprehensive examination of clinical and laboratory, such as bicytopenia (anemia and thrombocytopenia), acute renal failure, increased liver transaminase, and coagulation disorder (increased PT/APTT) D-dimer), hypoalbuminemia and extremely low CD4. Oral candidiasis, chronic B hepatitis, and lung tuberculosis also present as opportunistic infections in this patient. One dose of antiviral oseltamivir was given each day interval (considering the patient's renal function) accompanied with immediate resuscitation, multivitamins, fluconazole, and cotrimoxazole given. After resolving an acute condition, oral tuberculosis treatment was given, continued with antiretroviral therapy, and advised the patient to routine control in the outpatient department. Future research should address the significance of CD4 lymphocyte count or viral load to measure patients with HIV's immune system and clinical status, risk of opportunistic infection, and prognostic in this pandemic COVID-19 era.


COVID-19; HIV/AIDS; co-infection; multiple comorbidities

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